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Monday, January 21, 2013
Wednesday, January 2, 2013
What's Your Skin Eating?
The average woman wears nearly 515 chemicals a day. Nutra Relief Inc is creating for women non-pharmacetucial, non-chemical all natural creams that are extremely effective nutrient-rich formulations for your skin.
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Monday, December 3, 2012
View the full article of
Health Benefits of Melatonin below:
Health Benefits of Melatonin below:
MELATONIN
Melatonin
is widely known as a natural sleep-promoting compound, but research has shown
that melatonin offers other remarkable health promoting benefits.
Melatonin helps protect
against cancer
The
confirmed mechanisms of its cancer inhibitory abilities include:
Its ability to regulate estrogen receptor expression
and activation. Estrogens promote the growth of many types of tumors, like
breast ovarian, uterine and even prostate cancers.
· Its ability to modulate the production of estrogen.
· Its ability to activate cell mechanisms that promote cancer
cell death (apoptosis).
· Its ability to suppress the telomerase activity that makes
cancer cells immortal.
· Its ability to help prevent the spread of cancers throughout
the body (metastasis inhibition).
· Its ability to suppress the growth of blood vessels that
feed cancer tumors (anti-angiogenesis).
· Its ability to stimulate cell differentiation, which makes
cancer cells less “cancerous”.
· Its ability to stimulate immune system mechanisms that
suppress cancerous tumors.
· And by several other mechanisms including its antioxidant
effects.
Basic Mechanisms Involved in the Anti-Cancer Effects of
Melatonin; Current Medicinal Chemistry, 2010, 17, 4462-4481
Melatonin helps protect the skin
and supports skin health
Melatonin is naturally produced in the skin and offers many skin
protective effects. These include inhibiting the formation of wrinkles and
age spots, enhancing the elasticity of skin and ameliorating the effects of
sunburn by suppressing
ultraviolet-induced damage to skin cells. Melatonin “exhibits strong
antioxidant activity in cells exposed to ultraviolet radiation.”
On the Role of Melatonin in Skin Physiology and Pathology; Endocrine. 2005
July; 27(2): 137–148.
Melatonin offers many other health-promoting benefits
Research
also confirms the beneficial effects of melatonin as supportive (adjuvant)
therapy for a wide variety of conditions including:
· Macular degeneration, a common cause of vision loss
· Glaucoma, another common cause of vision loss
· Protection of the stomach lining (gastric mucosa)
· Irritable bowel syndrome
· Arterial hypertension (high blood pressure)
· Helping to lessen the side effects of chemotherapy and radiation in cancer patients
· Helping to lessen the side effects of hemodialysis in
patients with kidney disease
· Relief of sleep disorders, especially those that have to do
with the disruption of the normal sleep-wake cycle (trouble falling
asleep, jet-lag, shift changes and age-related sleep disorders including neurodegenerative conditions like Alzheimer’s
disease).
· Its additive benefits when used in anesthetic
procedures.
· Its ability to enhance the production of glutathione via a
variety of mechanisms including enhancing the expression and
activity of a variety of glutathione related enzymes. Glutathione is a
vitally important antioxidant and detoxifier which supports the health of
cells and tissues throughout the body.
Clinical Uses of Melatonin: Evaluation of Human Trials; Current Medicinal Chemistry,
2010, 17, 2070-2095.
The Glutathione System and its Regulation by Neurohormone
Melatonin in the Central Nervous System; Central Nervous System Agents in
Medicinal Chemistry, 2010, 10, 287-297 287
This product is not intended to diagnose, cure or treat cancer.
Melatonin has no adverse side effects or long-term
risks.
Friday, October 12, 2012
Health Benefits of
Arginine
By Harry Elwardt, N.D., Ph.D.C 2005 Arkworld International Inc. All rights reserved.
The following report, which is backed up by incredible scientific research, shows the many health benefits of increased arginine in the human body. Arginine is a semi-essential amino acid, which is produced in the liver and can be found in protein rich foods like red meat.
Aging Process
•
Arginine inhibits one of the primary mechanisms of the aging process as it
inhibits the process of
cross-linking
(1)
•
Arginine increases the release of the human growth hormone (HGH), also known as
the anti-aging
hormone,
from the pituitary gland (2)
Cardiovascular System
•
Arginine improves blood circulation, improves exercise capability and facilitates
vasodilation in
angina
patients (3)
•
Arginine helps to prevent atherosclerosis and reduces the severity of existing
atherosclerosis (4).
•
Arginine inhibits the adhesion of monocytes to the endothelium (an underlying
event in the course of
atherosclerosis)
(5)
•
Arginine improves blood circulation (by stimulating the production of nitric
oxide, an endogenous neurotransmitter that helps to prevent
vasoconstriction and which initiates vasodilation by relaxing the smooth
muscle cells of the blood vessels) (6)
•
Arginine helps to prevent abnormal blood clotting (by stimulating the
production of plasmin and by increasing vasodilation) (7)
•
Arginine helps to prevent free radicals-induced damage to the lining of blood
vessels (by enhancing the production of nitric oxide in blood vessels) (8)
•
Arginine significantly increases stroke volume and cardiac output (without
effect on heartbeat rate) in congestive heart failure patients. It also
increases vasodilation (leading to increased blood circulation) in
congestive heart failure patients (9)
•
Arginine reverses consequences of coronary heart disease (10)
•
Arginine lowers blood pressure in some hypertension patients (by facilitating
the body's production of nitric oxide (NO) and by inhibiting the angiotensin
converting enzyme (ACE)) (11)
•
Arginine reverses adverse effects of high blood pressure (12)
•
Arginine decreases high blood pressure (13).
•
Arginine reduces pulmonary blood pressure and improves blood circulation in
pulmonary
hypertension
patients (14)
•
Arginine increases walking distance in intermittent claudication patients (15)
•
Arginine restores normal endothelial function in hypercholesterolemia (16)
•
Arginine improves walking distance in peripheral vascular disease (17)
•
Arginine improves outcome after bypass surgery (18)
•
Arginine reduces blood clots and strokes (19)
•
Arginine helps prevent restenosis after angioplasty and bypass (20)
•
Arginine may give protection against size of heart attack (21)
•
Arginine improves heart failure (22)
•
Arginine improves peripheral vascular disease (23)
Digestive System
•
Arginine deficiency can cause constipation
•
Arginine supplementation may decrease the incidence of gallstones
•
Arginine reduces intestinal permeability (due to arginine’s role in the
production of nitric oxide) (2)
•
Arginine alleviates many cases of ulcerative colitis (by promoting the healing
of the ulcers that occur
in
the colon of ulcerative colitis patients) (25)
•
Arginine may improve irritable bowel syndrome (IBS) (26)
•
Arginine reduces ulcers (27).
•
Arginine helps prevent post surgical damage after intestinal manipulation (28)
•
Arginine improves outcome in sepis (29)
Excretory System
•
Arginine alleviates the pain and discomfort associated with interstitial
cystitis (30)
•
Arginine significantly improves the function of the kidneys and helps to
prevent age-related degradation of the kidneys (31)
Immune System
•
Arginine helps to prevent bacterial & viral diseases in persons with
suppressed immune systems
(32)
•
Arginine blocks the formation of some forms of cancer (arginine inhibits the
cellular replication of 24
different
types of cancer in animals) (33)
•
Arginine boosts the ability of the immune system to fight breast cancer (34)
•
Arginine lowers tumor protein synthesis and tumor growth rate in liver cancer
patients (35)
•
Arginine inhibits the further growth of some types of sarcomas (36)
•
One of the means by which arginine counteracts cancer is by reducing the
activity of ornithine decarboxylase, an enzyme that is associated with
some types of cancer. *Caution: Arginine is also speculated to exacerbate
some types of cancer, however this is not well proven.
•
Arginine improves outcome of cancer treatment (37)
•
Arginine (in non-excessive quantities) stimulates numerous aspects of the
immune system (38)
•
Arginine stimulates the production of helper T-cells (39)
•
Arginine stimulates the activity of lymphocytes and also stimulates their
production by the thymus
gland
(40)
•
Arginine increases the activity (cytotoxicity) of NK lymphocytes. (41)
•
Arginine stimulates the production of T-lymphocytes within the thymus and makes
them more active
and
effective (42)
•
Arginine increases the size of the thymus, stimulates the production of
lymphocytes by the thymus
and
restores the production of thymic hormones to youthful levels (43)
•
Arginine helps to counteract inflammation (44)
•
Arginine accelerates the ability of the immune system to recover from surgery
(45)
•
Arginine improves sickle cell disease (46)
Metabolism
•
Alkalosis can occur as a result of arginine deficiency (47)
•
Arginine exerts antioxidant effects that scavenge superoxide free radicals (48)
•
Arginine lowers total serum cholesterol levels (49)
•
Arginine lowers serum low-density lipoprotein (LDL) levels (50)
•
Arginine inhibits the process of cross-linking (51)
•
Arginine reduces insulin resistance and improves blood sugar disposal in
diabetes mellitus type 2
patients
(52)
•
Arginine reduces insulin resistance (53)
•
Arginine improves diabetes and reverses damage caused by diabetes (54)
•
Arginine may prevent diabetes (55)
•
Arginine increases oxygen uptake in the lungs in persons with hypoxia (due to
its role in the production of nitric oxide, which in turn improves blood
circulation via vasodilation) (56)
•
Arginine increases oxygen uptake in the lungs in persons with altitude sickness
(due to its role in the production of nitric oxide, which in turn improves
blood circulation via vasodilation) (57)
•
Arginine improves asthma (58)
•
Arginine helps to detoxify the liver and alleviates cirrhosis. Liver
malfunction can occur as a result of
arginine
deficiency (59)
•
Arginine lowers elevated serum triglyceride levels (60)
•
Arginine alleviates obesity and facilitates weight loss (by stimulating the
release of human growth hormone (HGH) from the pituitary gland) (61)
Musculoskeletal System
•
Arginine facilitates the healing of fractures (62)
•
Arginine facilitates muscle growth (by inhibiting muscle loss) and is required
for the transport of the nitrogen used in muscle metabolism (63)
•
Muscle weakness can occur as a result of arginine deficiency (64)
•
Arginine may prevent and alleviate osteoporosis (by stimulating the release of
human growth hormone (HGH) which is an important mediator of bone
formation and bone turnover; it also stimulates nitric oxide synthesis
which is a potent inhibitor of osteoclasts that cause the resorption
of bone) (65)
•
Arginine causes the relaxation of smooth muscle by functioning as a precursor
for nitric oxide production (66)
•
Arginine improves muscle performance (67)
•
Arginine improves glucose uptake into muscle cells (68)
Nervous System
•
Arginine may be useful for the treatment of Alzheimer’s disease due to its
ability to repair damaged axons by increasing polyamines levels (69)
•
Arginine is essential for the regeneration of damaged axons of neurons (its
role appears to be as an agent for degrading proteins that have been
damaged through axon injury) (70)
•
Arginine facilitates the potentiation of long-term memory (by stimulating the
production of nitric oxide (NO) - a neurotransmitter responsible for the
potentiation (storage) of long-term memory (71)
•
Arginine improves memory and cognitive functions (72)
•
Arginine improves pituitary responsiveness and modulates hormonal control (73)
Sexual System
•
Arginine alleviates male impotence (by stimulating the production of nitric
oxide, the endogenous chemical that stimulates erections in males) (74)
•
Arginine alleviates male infertility by improving sperm count and sperm
motility (due to its involvement in the manufacture of endogenous
spermidine) (75)
•
Arginine enhances (male and female) sexual desire (libido) (76)
•
Arginine enhances (female) sexual performance - due to its role in the
production of nitric oxide in the clitoris (nitric oxide facilitates
female orgasm in the clitoris) (77)
•
Arginine improves (male) sexual performance by providing nitrogen to the nitric
oxide (NO) molecule that is integral to the achievement of erections -
Arginine produces erections that are bigger, harder and more frequent. It
also increases male sexual endurance, i.e. erections that last for a
longer period of time (78)
•
Arginine improves sperm count and sperm motility (79)
•
Arginine may improve prostate function (80)
•
Arginine deficiency can cause atrophy of the testicles of the testes.
Skin/Hair
•
Hair loss (especially male pattern baldness) can occur as a result of arginine
deficiency (81)
•
Arginine concentrates in the skin
•
Arginine (applied topically) increases the level of vascular endothelial growth
factor in the skin (82)
•
Arginine stimulates the proliferation of fibroblasts (skin cells) (83)
•
Arginine is essential for and accelerates the healing of wounds (by stimulating
the release of human growth hormone (HGH), stimulating the production of
collagen and by stimulating the proliferation of fibroblasts) (84)
•
Arginine accelerates the healing of burns (85)
•
Arginine dramatically accelerates the healing of wounds in people who have
undergone surgery (86)
•
Arginine decreases postoperative infection and length of hospital stay (87)
•
Arginine improves scleroderma (88)
Safety
•
Arginine has been shown to be safe in the above studies as well as thousands of
others (89)
•
Arginine has been used safely in humans for the past 30 years. Thousands of
professional athletes, as well as non-athletes, have used arginine
supplements with no adverse side effects.
Research
1.
Radner, W., et al. L-arginine reduces kidney collagen accumulation and
N-epsilon-(carboxymethyl)lysine in the aging NMRI-mouse. J Gerontol.
49(2):M44-M46, 1994.
2.
Gianotti L, Macario M, Lanfranco F, et al. Arginine counteracts the inhibitory
effect of recombinant human insulin-like growth factor I on the
somatotroph responsiveness to growth hormone-releasing hormone in humans. J
Clin Endocrinol Metab 2000 Oct;85(10):3604-8.
3.
Ceremuzynski, L., et al. Effect of supplemental oral L-arginine on exercise
capacity in patients with stable angina pectoris. Am J Cardiol.
80:331-333, 1997.
4.
Adams, R. R., et al. Oral L-arginine improves endothelium-dependent dilatation
and reduces monocyte adhesion to endothelial cells in young men with
coronary artery disease. Atherosclerosis. 129(2):261-269, 1997.
5.
Adams, M. R., et al. Cigarette smoking is associated with increased human
monocyte adhesion to endothelial cells: reversibility with oral L-arginine
but not vitamin C. Journal of the American College of Cardiology.
29(3):491-497,
1997.
6.
Huk, I., et al. L-arginine treatment alters the kinetics of nitric oxide and
superoxide release and reduces ischemica/reperfusion injury in skeletal
muscle. Circulation. 96:667-675, 1997.
7.
Drexler H, et al. Correction of endothelial dysfunction in coronary
microcirculation of hypercholesterolaemic patients by L-arginine. The
Lancet. 338:1546-50, 1991.
8.
Huk, I., et al. L-arginine treatment alters the kinetics of nitric oxide and
superoxide release and reduces ischemica/reperfusion injury in skeletal
muscle. Circulation. 96:667-675, 1997.
9.
Koifman, B., et al. Improvement of cardiac performance by intravenous infusion
of l-arginine in patients with moderate congestive heart failure. Journal
of the American College of Cardiology. 26(5):1251-6, 1995.
10.
Quyyumi AA. Does acute improvement of endothelial dysfunction in coronary
arterydisease improve myocardial ischemia? J Am Coll Cardiol 1998
Oct;32(4):904-11.
11.
Khosh, F. Natural approach to hypertension. Alternative Medicine Review. 6(6),
2001.
12.
Sisic D, Francishetti A, Frolich ED. Prolonged L-arginine on cardiovascular
mass and myocardial hemodynamics and collagen in aged spontaneously
hypertensive and normal rats. Hypertension 1999 Jan;33(1 Pt 2):451-5.
13.
Nakaki T, et al. L-arginine induced hypotension. Lancet 1990Oct 20;
336(8721):1016-7.
14.
Nagaya, N., et al. Short-term oral administration of L-arginine improves
hemodynamics and exercise capacity in patients
with
precapillary pulmonary hypertension. Am J Resp Crit Care Med. 163(4):887-891,
2001.
15.
Roberts, A. J., et al. Nutraceuticals: The Complete Encyclopedia of
Supplements, Herbs, Vitamins and Healing Foods. Berkely Publishing Group.
New York, USA. 2001:319.
16.
Maxwell AJ, Anderson B Zapien MP, Cooke JP. Endothelial dysfunction in
hypercholesterolemia is reversed by: nutritional product designed to
enhance nitric oxide activity. Cardiovasc Drugs Ther 2000 Jun;14(3):309-16.
17.
Maxwell AJ, Anderson BE Cooke JP. Nutritional therapy for peripheral artery
disease. Vasc Med 2000;5(1):11-19.
18.
Wallace AW, Ratcliffe MB, Galindez D, Kong JS. L-arginine infusion dilates
coronary vasculature in patients undergoing coronary bypass surgery
Aenesthesiology 1999 Jun;90(6):1577-8.
19.
Bode-Boger SM, Boger RH, et al. Differential inhibition of human platelet
aggregation and thromboxane A 2 formation by L-arginine in vivo and in
vitro. Arch Pharmacol 1998; 357:143-150. Health benefits of Arginine by Dr
Harry Elwardt 12/08/2006 C 2005 Arkworld International Inc. All rights
reserved. Page 5 of 6
20.
Le Yorneau T, Van Belle E, Corseaux D, et al . Role of nitric oxide in
re-stenosis after experimental balloon angioplasty in the
hypercholesterolemic rabbit. J Am CollCardiol 1999 Mar;33(3):876-82.
21.
Suematsu Y, Ohtsuka T, et al. L-Arginine given after ischemic preconditioning
can enhance cardioprotection in isolated
rat
hearts. Eur J Cardiothorac Surg 2001, Jun;19(6):873-9.
22.
Hambrecht R, et al. Correction of endothelial dysfunction in chronic heart
failure: additional effects of exercise training
and
oral L-arginine supplementation. J Am Coll Cardiol 2000 Mar 1; 35(3):706-13.
23.
Bode-Boger SM, Boger RH,et al. L-arginine induces nitric oxide-dependent
vasodilation in patients with critical limb ischemia. A randomized,
controlled study. Circulation 1996 Jan 1; 93(1):85-90.
24.
Miller, A. L. The pathogenesis, clinical implications, and treatment of
intestinal hyperpermeability. Alternative Medicine Review. 2(5):330-345,
1997.
25.
Segala, M. (editor). Disease Prevention and Treatment 3rd Edition. Life
Extension Media. Florida, USA. 2000:202.
26.
Sahin AS, Atalik KE, Gunel E, Dogan N. Nonadrenergic, noncholinergic responses
of the human colon smooth muscle and the role of K+channels in these
responses. Methods Find Exp Clin Pharmacol 2001 Jan-Feb;23(1):13-7.
27.
Khattab MM, Gad MZ, Abdallah D. Protective role of nitric oxide in
indomethacin- induced gastric ulceration by a mechanism independent of
gastric acid secretion. Pharmacol Res 2001 May;43(5):463-7.
28.
Thomas S, Ramachandran A, Patra S, et al. Nitric oxide protects the intestine
from the damage induced by laparotomy and gut manipulation. J Surg Res
2001 Jul;99(1):25-32.
29.
Vallet B. Microthrombosis in sepsis. Minerva Anestesiol 2001 Apr;67(4):298-301.
30.
Smith, S. D., et al. Improvement in interstitial cystitis symptoms scores
during treatment with oral L-arginine. J Urol. 158(3 Part 1):703-708,
1997.
31.
Reckelhoff, J. F., et al. Long-term dietary supplementation with L-arginine
prevents age-related reduction in renal
function.
Am J Physiol. 272(6 Part 2):R1768-R1774, 1997.
32.
Field, C. J., et al. Glutamine and arginine: immunonutrients for improved
health. Med Sci Sports Exerc. 32:(Suppl) S377-88, 2000.
33.
Reynolds, J., et al. Immunologic effects of arginine supplementation in
tumor-bearing and non-tumor-bearing hosts. Annals of Surgery. 211:202-209,
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34.
Cha-Chung, Y. Arrest of mammary tumor growth by l-arginine. Biochemical and
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35.
Weisburger, J. Prevention by arginine glutamate of the carcinogenicity of
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36.
Rettura, G., et al. Supplemental arginine increases thymic cellularity in
normal and murine sarcoma virus-inoculated mice and increases the
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37.
Heys SD, et al. Dietary supplementation with L-arginine: Modulation of tumor
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38.
Kirk, S. J., et al. Arginine stimulates wound healing and immune function in
elderly human beings. Surgery. 114(2):155-159, 1993.
39.
Blechman, S., et al. L-arginine boosts the immune system. Muscular Development.
38(10):72, 2001.
40.
Barbul, A., et al. Arginine stimulates lymphocyte immune response in healthy
human beings. Surgery. 90:224-251,1981.
41.
Ochoa, J. B., et al. Effects of L-arginine on the proliferation of T lymphocyte
subpopulations. J Parenteral Enteral Nutr. 25:23-29, 2001.
42.
Moriguchi, S., et al. Functional changes in human lymphocytes and monocytes
after in vitro incubation with arginine. Nutrition Research. 7:719-729,
1987.
43.
Dean, W. The neuroendocrine theory of aging part IV: the immune homeostat.
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44.
Efron, D. T., et al. Modulation of inflammation and immunity by arginine
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45.
Wilmore, D. W. The effect of glutamine supplementation in patients following
elective surgery and accidental injury. Journal of Nutrition.
131(Supplement):2543S-2549S, 2001.
46.
Morric CR, Kuypers FA, et al. Patterns of arginine and nitric oxide in patients
with sickle cell disease with vaso-occlusive crisis and acute chest
syndrome. J Ped Hemat/Onc 2000 Nov-Dec;22(6):515-20.
47.
Braverman, Eric R. The Healing Nutrients Within. Keats Publishing, New Canaan,
Connecticut, USA. 1997:221.
48.
Wascher, T. C., et al. Vascular effects of L-arginine: Anything beyond a
substrate for NO synthase? Biochem Biophys Res Com. 234:35-38, 1997.
49.
Rossitch E, Jr., et al. L-arginine normalizes endothelial function in cerebral
vessels from hypercholesterolemic rabbits.
Journal
of Clinical Investigation. 87(4):1295-1299, 1991.
50.
Ryzenhov, V. E., et al. Action of arginine on the lipid and lipoprotein content
in blood serum of animals. Voprosy Meditsinskoi Khimi. 30(6):76-80, 1984.
51.
Radner, W., et al. L-arginine reduces kidney collagen accumulation and
N-epsilon-(carboxymethyl)lysine in the aging NMRI-mouse. J Gerontol.
49(2):M44-M46, 1994.
52.
Piatti, P. M., et al. Long-term oral L-arginine administration improves
peripheral and hepatic insulin sensitivity in type 2 diabetic patients.
Diabetes Care. 24(5):875-880, 2001.
53.
Wascher, T. C., et al. Effects of low-dose L-arginine on insulin mediated
vasodilation and insulin sensitivity. Eur J Clin Invest. 27:690-695, 1997.
54.
Giugliana D, et al. Vascular effects of acute hyperglycemia are reversed by
L-arginine. Circulation 1997; 95(7):1783-90. Health benefits of Arginine
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rights reserved. Page 6 of 6
55.
Mohan IK, Cas UN. Effects of L-arginine-nitric oxide system on chemical induced
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56.
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57.
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414(6862):411-412, 2001.
58.
De Gouw HW, Verbruggen MB, Twiss IM, Sterk PJ. Effect of oral L-arginine on
airway hyper-responsiveness to histamine in asthma. Thorax 1999
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61.
Gianotti L, Macario M, Lanfranco F, et al. Arginine counteracts the inhibitory
effect of recombinant human insulin-like growth factor I on the somatotroph
responsiveness to growth hormone-releasing hormone in humans. J Clin
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62.
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74.
Chen, J., et al. Effect of oral administration of high-dose nitric oxide donor
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